4PIY

Homocysteine bound Cysteine Dioxygenase C93A variant at pH 6.2

4PIY の概要

• エントリーDOI: 10.2210/pdb4piy/pdb
• 関連するPDBエントリー: 4IEO 4IEP 4IEQ 4IER 4IES 4IET 4IEU 4IEV 4IEW 4IEX 4IEY 4IEZ 4JTN 4JTO
• 分子名称: Cysteine dioxygenase type 1, FE (III) ION, 2-AMINO-4-MERCAPTO-BUTYRIC ACID, ... (4 entities in total)
• 機能のキーワード: cupin fold, catalyzes oxidation, cysteine to cysteine sulfinate, c93-y157 crosslink, cytosol, oxidoreductase
• 由来する生物種: Rattus norvegicus (Rat)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23217.85

構造登録者

Driggers, C.M.,Karplus, P.A. (登録日: 2014-05-09, 公開日: 2016-02-17, 最終更新日: 2024-04-03)

• 主引用文献: Driggers, C.M.,Kean, K.M.,Hirschberger, L.L.,Cooley, R.B.,Stipanuk, M.H.,Karplus, P.A.; Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase.; J. Mol. Biol., 428:3999-4012, 2016; PubMed: 27477048; DOI: 10.1016/j.jmb.2016.07.012

実験手法

X-RAY DIFFRACTION (1.6 Å)