4PAX

THE CATALYTIC FRAGMENT OF POLY(ADP-RIBOSE) POLYMERASE COMPLEXED WITH 8-HYDROXY-2-METHYL-3-HYDRO-QUINAZOLIN-4-ONE

4PAX の概要

• エントリーDOI: 10.2210/pdb4pax/pdb
• 分子名称: POLY(ADP-RIBOSE) POLYMERASE, 8-HYDROXY-2-METHYL-3-HYDRO-QUINAZOLIN-4-ONE (3 entities in total)
• 機能のキーワード: transferase, glycosyltransferase, nad(+) adp-ribosyltransferase
• 由来する生物種: Gallus gallus (chicken)
• 細胞内の位置: Nucleus: P26446
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 40591.52

構造登録者

Ruf, A.,Schulz, G.E. (登録日: 1997-11-25, 公開日: 1998-05-27, 最終更新日: 2023-08-09)

• 主引用文献: Ruf, A.,de Murcia, G.,Schulz, G.E.; Inhibitor and NAD+ binding to poly(ADP-ribose) polymerase as derived from crystal structures and homology modeling.; Biochemistry, 37:3893-3900, 1998; PubMed: 9521710; DOI: 10.1021/bi972383s

実験手法

X-RAY DIFFRACTION (2.8 Å)