4P6P

Structure of ribB complexed with inhibitor (4PEH) and metal ions

Summary for 4P6P

• Entry DOI: 10.2210/pdb4p6p/pdb
• Related: 4P6C 4P6D 4P77
• Descriptor: 3,4-dihydroxy-2-butanone 4-phosphate synthase, 4-PHOSPHO-D-ERYTHRONOHYDROXAMIC ACID, ZINC ION, ... (4 entities in total)
• Functional Keywords: ribb, riboflvain, ligand, complex, crystal, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Vibrio cholerae serotype O1
• Total number of polymer chains: 2
• Total formula weight: 52530.19

Authors

Islam, Z.,Kumar, A.,Singh, S.,Salmon, L.,Karthikeyan, S. (deposition date: 2014-03-25, release date: 2015-03-25, Last modification date: 2023-09-27)

• Primary citation: Islam, Z.,Kumar, A.,Singh, S.,Salmon, L.,Karthikeyan, S.; Structural Basis for Competitive Inhibition of 3,4-Dihydroxy-2-butanone-4-phosphate Synthase from Vibrio cholerae.; J.Biol.Chem., 290:11293-11308, 2015; PubMed: 25792735; DOI: 10.1074/jbc.M114.611830

Experimental method

X-RAY DIFFRACTION (1.862 Å)