4P54

Crystal Structure of the Helicobacter pylori MTAN-D198N mutant with 5'-methylthioadenosine in the active site.

Summary for 4P54

Entry DOI	10.2210/pdb4p54/pdb
Related	3NM4 3NM5 3NM6 4OJT 4OY3
Descriptor	Aminodeoxyfutalosine nucleosidase, 5'-DEOXY-5'-METHYLTHIOADENOSINE, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	homodimer, hydrolase
Biological source	Helicobacter pylori
Total number of polymer chains	1
Total formula weight	25438.75
Authors	Ronning, D.R.,Mishra, V. (deposition date: 2014-03-14, release date: 2014-04-02, Last modification date: 2023-09-27)
Primary citation	Mishra, V.,Ronning, D.R. Crystal structures of the Helicobacter pylori MTAN enzyme reveal specific interactions between S-adenosylhomocysteine and the 5'-alkylthio binding subsite. Biochemistry, 51:9763-9772, 2012 Cited by PubMed: 23148563 DOI: 10.1021/bi301221k PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation