4OVG

E. coli sliding clamp in complex with (R)-9-(2-amino-2-oxoethyl)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid

4OVG の概要

• エントリーDOI: 10.2210/pdb4ovg/pdb
• 関連するPDBエントリー: 4OVF 4OVH 4PNU 4PNV 4PNW
• 分子名称: DNA polymerase III subunit beta, (2R)-9-(2-amino-2-oxoethyl)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid, DI(HYDROXYETHYL)ETHER, ... (9 entities in total)
• 機能のキーワード: poliii beta, sliding clamp, dnan, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 83130.90

構造登録者

Yin, Z.,Oakley, A.J. (登録日: 2014-02-21, 公開日: 2014-03-05, 最終更新日: 2024-02-28)

• 主引用文献: Yin, Z.,Whittell, L.R.,Wang, Y.,Jergic, S.,Ma, C.,Lewis, P.J.,Dixon, N.E.,Beck, J.L.,Kelso, M.J.,Oakley, A.J.; Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs.; J.Med.Chem., 58:4693-4702, 2015; PubMed: 25970224; DOI: 10.1021/acs.jmedchem.5b00232

実験手法

X-RAY DIFFRACTION (1.9 Å)