4OTN

Crystal structure of the C-terminal regulatory domain of murine GCN2

Summary for 4OTN

• Entry DOI: 10.2210/pdb4otn/pdb
• Related: 4OTM
• Descriptor: Eukaryotic translation initiation factor 2-alpha kinase 4, SULFATE ION, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: c-terminal regulatory domain, gcn2, 4-stranded beta sheet 3 helix bundle, regulatory domain of eif2 stress kinase, transferase
• Biological source: Mus musculus (mouse)
• Cellular location: Cytoplasm : Q9QZ05
• Total number of polymer chains: 2
• Total formula weight: 31996.50

Authors

He, H.,Georgiadis, M.M. (deposition date: 2014-02-13, release date: 2014-04-16, Last modification date: 2024-02-28)

• Primary citation: He, H.,Singh, I.,Wek, S.A.,Dey, S.,Baird, T.D.,Wek, R.C.,Georgiadis, M.M.; Crystal Structures of GCN2 Protein Kinase C-terminal Domains Suggest Regulatory Differences in Yeast and Mammals.; J.Biol.Chem., 289:15023-15034, 2014; PubMed: 24719324; DOI: 10.1074/jbc.M114.560789

Experimental method

X-RAY DIFFRACTION (1.9 Å)