4OTD
Crystal Structure of PRK1 Catalytic Domain
Summary for 4OTD
Entry DOI | 10.2210/pdb4otd/pdb |
Related | 4OTG 4OTH 4OTI |
Descriptor | Serine/threonine-protein kinase N1 (2 entities in total) |
Functional Keywords | prk1, pkn1, protein kinase c related kinase 1, kinase, protein kinase, atp binding, phosphorylation, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : Q16512 |
Total number of polymer chains | 1 |
Total formula weight | 38341.50 |
Authors | Chamberlain, P.P.,Delker, S.,Pagarigan, B.,Mahmoudi, A.,Jackson, P.,Abbassian, M.,Muir, J.,Raheja, N.,Cathers, B. (deposition date: 2014-02-13, release date: 2014-08-27, Last modification date: 2018-01-24) |
Primary citation | Chamberlain, P.,Delker, S.,Pagarigan, B.,Mahmoudi, A.,Jackson, P.,Abbasian, M.,Muir, J.,Raheja, N.,Cathers, B. Crystal Structures of PRK1 in Complex with the Clinical Compounds Lestaurtinib and Tofacitinib Reveal Ligand Induced Conformational Changes. Plos One, 9:e103638-e103638, 2014 Cited by PubMed: 25111382DOI: 10.1371/journal.pone.0103638 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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