4OSP
The crystal structure of urdamycin C-6 ketoreductase domain UrdMred with bound NADP and rabelomycin
Summary for 4OSP
| Entry DOI | 10.2210/pdb4osp/pdb |
| Related | 4OSO |
| Descriptor | Oxygenase-reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, rabelomycin, ... (4 entities in total) |
| Functional Keywords | rossmann fold, ketoreductase, nadph binding, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase-antibiotic complex, oxidoreductase/antibiotic |
| Biological source | Streptomyces fradiae |
| Total number of polymer chains | 4 |
| Total formula weight | 112395.62 |
| Authors | Niiranen, L.,Paananen, P.,Patrikainen, P.,Metsa-Ketela, M. (deposition date: 2014-02-13, release date: 2014-10-01, Last modification date: 2023-09-20) |
| Primary citation | Patrikainen, P.,Niiranen, L.,Thapa, K.,Paananen, P.,Tahtinen, P.,Mantsala, P.,Niemi, J.,Metsa-Ketela, M. Structure-based engineering of angucyclinone 6-ketoreductases. Chem.Biol., 21:1381-1391, 2014 Cited by PubMed: 25200607DOI: 10.1016/j.chembiol.2014.07.017 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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