4ORC

Crystal structure of mammalian calcineurin

Summary for 4ORC

Related4ORA 4ORB 4OR9
DescriptorSerine/threonine-protein phosphatase 2B catalytic subunit beta isoform, Calcineurin subunit B type 1, ZINC ION, ... (7 entities in total)
Functional Keywordscalmodulin-binding, hydrolase-metal binding protein complex, hydrolase/metal binding protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, cytosol  P63098
Total number of polymer chains2
Total molecular weight80963.91
Authors
Ma, L.,Li, S.J.,Wang, J.,Wu, J.W.,Wang, Z.X. (deposition date: 2014-02-11, release date: 2015-05-20, Last modification date: 2016-12-21)
Primary citation
Li, S.J.,Ma, L.,Wang, J.,Lu, C.,Wang, J.,Wu, J.W.,Wang, Z.X.
Cooperative autoinhibition and multi-level activation mechanisms of calcineurin
To be Published,
Experimental method
X-RAY DIFFRACTION (2.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.254608.4%1.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report