4OP0

Crystal structure of biotin protein ligase (RV3279C) of Mycobacterium tuberculosis, complexed with biotinyl-5'-AMP

Summary for 4OP0

Entry DOI	10.2210/pdb4op0/pdb
Descriptor	BirA bifunctional protein, BIOTINYL-5-AMP, SULFATE ION, ... (4 entities in total)
Functional Keywords	bira, ligase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	2
Total formula weight	57745.36
Authors	Ma, Q.,Wilmanns, M.,Akhter, Y. (deposition date: 2014-02-04, release date: 2014-04-30, Last modification date: 2023-09-20)
Primary citation	Ma, Q.,Akhter, Y.,Wilmanns, M.,Ehebauer, M.T. Active site conformational changes upon reaction intermediate biotinyl-5'-AMP binding in biotin protein ligase from Mycobacterium tuberculosis. Protein Sci., 23:932-939, 2014 Cited by PubMed: 24723382 DOI: 10.1002/pro.2475 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation