4OKA

Structural-, Kinetic- and Docking Studies of Artificial Imine Reductases Based on the Biotin-Streptavidin Technology: An Induced Lock-and-Key Hypothesis

4OKA の概要

• エントリーDOI: 10.2210/pdb4oka/pdb
• 分子名称: Streptavidin, [N-(4-{[2-(amino-kappaN)ethyl]sulfamoyl-kappaN}phenyl)-5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamidato]iridium(III), IRIDIUM ION, ... (4 entities in total)
• 機能のキーワード: beta barrel, transfer hydrogenation, iridium piano stool, biotin-binding protein
• 由来する生物種: Streptomyces avidinii
• 細胞内の位置: Secreted: P22629
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 17437.11

構造登録者

Schirmer, T.,Heinisch, T. (登録日: 2014-01-22, 公開日: 2014-11-05, 最終更新日: 2023-11-08)

• 主引用文献: Robles, V.M.,Durrenberger, M.,Heinisch, T.,Lledos, A.,Schirmer, T.,Ward, T.R.,Marechal, J.D.; Structural, Kinetic, and Docking Studies of Artificial Imine Reductases Based on Biotin-Streptavidin Technology: An Induced Lock-and-Key Hypothesis; J.Am.Chem.Soc., 136:15676-15683, 2014; PubMed: 25317660; DOI: 10.1021/ja508258t

実験手法

X-RAY DIFFRACTION (2.505 Å)