4OIG

Dengue Virus Non-structural Protein NS1

4OIG の概要

• エントリーDOI: 10.2210/pdb4oig/pdb
• 関連するPDBエントリー: 4OIE 4OII
• 分子名称: Non-structural protein 1, NS1, SULFATE ION (3 entities in total)
• 機能のキーワード: dengue virus, non-structural protein, ns1, flavivirus viral protein, structural genomics, center for structural genomics of infectious diseases, csgid, viral protein
• 由来する生物種: Dengue virus 1 (DENV-1)
• 細胞内の位置: Capsid protein C: Virion. Peptide pr: Secreted . Small envelope protein M: Virion membrane ; Multi-pass membrane protein . Envelope protein E: Virion membrane ; Multi-pass membrane protein . Non-structural protein 1: Secreted . Non-structural protein 2A: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Serine protease subunit NS2B: Host endoplasmic reticulum membrane; Multi-pass membrane protein . Serine protease NS3: Host endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Non-structural protein 4A: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Non-structural protein 4B: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . RNA-directed RNA polymerase NS5: Host endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side : P17763
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 86790.26

構造登録者

Edeling, M.A.,Fremont, D.H.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2014-01-19, 公開日: 2014-03-05, 最終更新日: 2017-11-22)

• 主引用文献: Edeling, M.A.,Diamond, M.S.,Fremont, D.H.; Structural basis of Flavivirus NS1 assembly and antibody recognition.; Proc.Natl.Acad.Sci.USA, 111:4285-4290, 2014; PubMed: 24594604; DOI: 10.1073/pnas.1322036111

実験手法

X-RAY DIFFRACTION (2.69 Å)