Summary for 4OEW
Entry DOI | 10.2210/pdb4oew/pdb |
Related | 4OEX |
Descriptor | cGMP-specific 3',5'-cyclic phosphodiesterase, ZINC ION, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 40727.23 |
Authors | Chen, T.T.,Ren, J.,Xu, Y.C. (deposition date: 2014-01-14, release date: 2015-04-01, Last modification date: 2024-02-28) |
Primary citation | Ren, J.,He, Y.,Chen, W.,Chen, T.,Wang, G.,Wang, Z.,Xu, Z.,Luo, X.,Zhu, W.,Jiang, H.,Shen, J.,Xu, Y. Thermodynamic and structural characterization of halogen bonding in protein-ligand interactions: a case study of PDE5 and its inhibitors. J.Med.Chem., 57:3588-3593, 2014 Cited by PubMed: 24702184DOI: 10.1021/jm5002315 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.44 Å) |
Structure validation
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