4OEG
Crystal Structure Analysis of FGF2-Disaccharide (S9I2) complex
Summary for 4OEG
Entry DOI | 10.2210/pdb4oeg/pdb |
Related | 4OEE 4OEF |
Descriptor | Fibroblast growth factor 2, 2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid (3 entities in total) |
Functional Keywords | heparin/heparin sulfate binding, protein binding |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 17939.31 |
Authors | Li, Y.C.,Hsiao, C.D. (deposition date: 2014-01-13, release date: 2014-07-09, Last modification date: 2023-09-20) |
Primary citation | Li, Y.C.,Ho, I.H.,Ku, C.C.,Zhong, Y.Q.,Hu, Y.P.,Chen, Z.G.,Chen, C.Y.,Lin, W.C.,Zulueta, M.M.,Hung, S.C.,Lin, M.G.,Wang, C.C.,Hsiao, C.D. Interactions that influence the binding of synthetic heparan sulfate based disaccharides to fibroblast growth factor-2. Acs Chem.Biol., 9:1712-1717, 2014 Cited by PubMed: 24959968DOI: 10.1021/cb500298q PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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