4OAR
Progesterone receptor with bound ulipristal acetate and a peptide from the co-repressor SMRT
Summary for 4OAR
Entry DOI | 10.2210/pdb4oar/pdb |
Descriptor | Progesterone receptor, Peptide from Nuclear receptor corepressor 2, [(8S,11R,13S,14S,17R)-17-acetyl-11-[4-(dimethylamino)phenyl]-13-methyl-3-oxo-1,2,6,7,8,11,12,14,15,16-decahydrocyclopen ta[a]phenanthren-17-yl] acetate, ... (4 entities in total) |
Functional Keywords | progesterone receptor, steroid receptor, nuclear receptor, transcription factor, women health, contraception, transcription-peptide complex, transcription/peptide |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus. Isoform A: Nucleus. Isoform 4: Mitochondrion outer membrane: P06401 Nucleus: Q9Y618 |
Total number of polymer chains | 2 |
Total formula weight | 32086.73 |
Authors | Petit-Topin, I.,Fay, M.R.,Resche-Rigon, M.,Ulmann, A.,Gainer, E.,Rafestin-Oblin, M.-E.,Fagart, J. (deposition date: 2014-01-06, release date: 2014-10-08, Last modification date: 2023-09-20) |
Primary citation | Petit-Topin, I.,Fay, M.,Resche-Rigon, M.,Ulmann, A.,Gainer, E.,Rafestin-Oblin, M.E.,Fagart, J. Molecular determinants of the recognition of ulipristal acetate by oxo-steroid receptors. J.Steroid Biochem.Mol.Biol., 144PB:427-435, 2014 Cited by PubMed: 25204619DOI: 10.1016/j.jsbmb.2014.08.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.41 Å) |
Structure validation
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