4O51
Crystal structure of the QAA variant of anti-hinge rabbit antibody 2095-2 in complex with IDES hinge peptide
Summary for 4O51
Entry DOI | 10.2210/pdb4o51/pdb |
Related | 4MA3 4O4Y |
Descriptor | QAA-2095-2 light chain, QAA-2095-2 heavy chain, IDES hinge peptide, ... (4 entities in total) |
Functional Keywords | immunoglobulin fold, antibody, hinge, immune system |
Biological source | Oryctolagus cuniculus, Homo sapiens (rabbit, human) More |
Total number of polymer chains | 12 |
Total formula weight | 192622.09 |
Authors | Malia, T.J.,Luo, J.,Teplyakov, A.,Gilliland, G.L. (deposition date: 2013-12-19, release date: 2014-03-26, Last modification date: 2023-09-20) |
Primary citation | Malia, T.J.,Teplyakov, A.,Brezski, R.J.,Luo, J.,Kinder, M.,Sweet, R.W.,Almagro, J.C.,Jordan, R.E.,Gilliland, G.L. Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge. Proteins, 82:1656-1667, 2014 Cited by PubMed: 24638881DOI: 10.1002/prot.24545 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.204 Å) |
Structure validation
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