4O51

Crystal structure of the QAA variant of anti-hinge rabbit antibody 2095-2 in complex with IDES hinge peptide

Summary for 4O51

• Entry DOI: 10.2210/pdb4o51/pdb
• Related: 4MA3 4O4Y
• Descriptor: QAA-2095-2 light chain, QAA-2095-2 heavy chain, IDES hinge peptide, ... (4 entities in total)
• Functional Keywords: immunoglobulin fold, antibody, hinge, immune system
• Biological source: Oryctolagus cuniculus, Homo sapiens (rabbit, human); More
• Total number of polymer chains: 12
• Total formula weight: 192622.09

Authors

Malia, T.J.,Luo, J.,Teplyakov, A.,Gilliland, G.L. (deposition date: 2013-12-19, release date: 2014-03-26, Last modification date: 2023-09-20)

• Primary citation: Malia, T.J.,Teplyakov, A.,Brezski, R.J.,Luo, J.,Kinder, M.,Sweet, R.W.,Almagro, J.C.,Jordan, R.E.,Gilliland, G.L.; Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge.; Proteins, 82:1656-1667, 2014; PubMed: 24638881; DOI: 10.1002/prot.24545

Experimental method

X-RAY DIFFRACTION (2.204 Å)