4O3F
Crystal Structure of mouse PGK1 3PG and terazosin(TZN) ternary complex
Summary for 4O3F
Entry DOI | 10.2210/pdb4o3f/pdb |
Related | 4O33 |
Descriptor | Phosphoglycerate kinase 1, [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl][(2R)-tetrahydrofuran-2-yl]methanone, 3-PHOSPHOGLYCERIC ACID, ... (4 entities in total) |
Functional Keywords | enzyme-drug complex, transferase-transferase activator complex, transferase/transferase activator |
Biological source | Mus musculus (mouse) |
Cellular location | Cytoplasm : P09411 |
Total number of polymer chains | 1 |
Total formula weight | 45180.89 |
Authors | Li, X.L.,Finci, I.L.,Wang, J.H. (deposition date: 2013-12-18, release date: 2014-10-29, Last modification date: 2023-09-20) |
Primary citation | Chen, X.,Zhao, C.,Li, X.,Wang, T.,Li, Y.,Cao, C.,Ding, Y.,Dong, M.,Finci, L.,Wang, J.H.,Li, X.,Liu, L. Terazosin activates Pgk1 and Hsp90 to promote stress resistance. Nat.Chem.Biol., 11:19-25, 2015 Cited by PubMed: 25383758DOI: 10.1038/nchembio.1657 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.106 Å) |
Structure validation
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