4NZV

DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities

Summary for 4NZV

• Entry DOI: 10.2210/pdb4nzv/pdb
• Descriptor: Exonuclease, putative, MANGANESE (II) ION (3 entities in total)
• Functional Keywords: dna repair mre11 thermophilic nuclease, dna double-strand break repair, hydrolase
• Biological source: Thermotoga maritima
• Total number of polymer chains: 2
• Total formula weight: 77370.18

Authors

Shibata, A.,Moiani, D.,Arvai, A.S.,Perry, J.,Harding, S.M.,Genois, M.,Maity, R.,Rossum-Fikkert, S.,Kertokalio, A.,Romoli, F.,Ismail, A.,Ismalaj, E.,Petricci, E.,Neale, M.J.,Bristow, R.G.,Masson, J.,Wyman, C.,Jeggo, P.A.,Tainer, J.A. (deposition date: 2013-12-12, release date: 2014-01-08, Last modification date: 2024-02-28)

• Primary citation: Shibata, A.,Moiani, D.,Arvai, A.S.,Perry, J.,Harding, S.M.,Genois, M.M.,Maity, R.,van Rossum-Fikkert, S.,Kertokalio, A.,Romoli, F.,Ismail, A.,Ismalaj, E.,Petricci, E.,Neale, M.J.,Bristow, R.G.,Masson, J.Y.,Wyman, C.,Jeggo, P.A.,Tainer, J.A.; DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities.; Mol.Cell, 53:7-18, 2014; PubMed: 24316220; DOI: 10.1016/j.molcel.2013.11.003

Experimental method

X-RAY DIFFRACTION (1.901 Å)