4NUX
Structure of receptor A
Summary for 4NUX
Entry DOI | 10.2210/pdb4nux/pdb |
Descriptor | Interleukin-17 receptor A (2 entities in total) |
Functional Keywords | sefir domain, immune system, cytokine, receptor, autoimmune inflammatory |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 1: Membrane; Single-pass type I membrane protein (By similarity). Isoform 2: Secreted: Q96F46 |
Total number of polymer chains | 1 |
Total formula weight | 24771.56 |
Authors | |
Primary citation | Zhang, B.,Liu, C.,Qian, W.,Han, Y.,Li, X.,Deng, J. Structure of the unique SEFIR domain from human interleukin 17 receptor A reveals a composite ligand-binding site containing a conserved alpha-helix for Act1 binding and IL-17 signaling. Acta Crystallogr.,Sect.D, 70:1476-1483, 2014 Cited by PubMed: 24816115DOI: 10.1107/S1399004714005227 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.295 Å) |
Structure validation
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