4NG2

Crystal structure of LasR LBD-QslA complex from Pseudomonas aeruginosa

Summary for 4NG2

Entry DOI	10.2210/pdb4ng2/pdb
Descriptor	Transcriptional activator protein LasR, Uncharacterized protein, N-3-OXO-DODECANOYL-L-HOMOSERINE LACTONE, ... (4 entities in total)
Functional Keywords	quorum sensing, antiactivator, transcription regulator
Biological source	Pseudomonas aeruginosa More
Total number of polymer chains	12
Total formula weight	185887.53
Authors	Fan, H.,Wu, D.H.,Song, H. (deposition date: 2013-11-01, release date: 2013-12-18, Last modification date: 2023-11-08)
Primary citation	Fan, H.,Dong, Y.,Wu, D.H.,Bowler, M.W.,Zhang, L.,Song, H. QsIA disrupts LasR dimerization in antiactivation of bacterial quorum sensing Proc.Natl.Acad.Sci.USA, 110:20765-20770, 2013 Cited by PubMed: 24319092 DOI: 10.1073/pnas.1314415110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.413 Å)

Structure validation