4NCI

Crystal Structure of Pyrococcus furiosis Rad50 R805E mutation

Summary for 4NCI

Related4NCH 4NCJ 4NCK
DescriptorDNA double-strand break repair Rad50 ATPase (2 entities in total)
Functional Keywordsadenosine triphosphatase, dna repair, dna binding protein, fungal protein
Biological sourcePyrococcus furiosus
Total number of polymer chains1
Total molecular weight38580.54
Authors
Classen, S.,Williams, G.J.,Arvai, A.S.,Williams, R.S. (deposition date: 2013-10-24, release date: 2014-03-05, Last modification date: 2017-08-02)
Primary citation
Deshpande, R.A.,Williams, G.J.,Limbo, O.,Williams, R.S.,Kuhnlein, J.,Lee, J.H.,Classen, S.,Guenther, G.,Russell, P.,Tainer, J.A.,Paull, T.T.
ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.
Embo J., 33:482-500, 2014
PubMed: 24493214 (PDB entries with the same primary citation)
DOI: 10.1002/embj.201386100
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.26510.3%3.7%7.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report