4N8V
Crystal structure of killer cell immunoglobulin-like receptor KIR2DS2 in complex with HLA-A
Summary for 4N8V
Entry DOI | 10.2210/pdb4n8v/pdb |
Descriptor | Killer cell immunoglobulin-like receptor 2DS2, HLA class I histocompatibility antigen, A-11 alpha chain, Beta-2-microglobulin, ... (5 entities in total) |
Functional Keywords | antigen presentation, cell lysing, kir binding, membrane, kir2ds2, activating kir, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P43631 Secreted: P13746 Virion membrane; Multi-pass membrane protein (Potential): P61769 Cell membrane; Single-pass type I membrane protein: Q76ZQ3 |
Total number of polymer chains | 8 |
Total formula weight | 133829.00 |
Authors | |
Primary citation | Liu, J.X.,Xiao, Z.W.,Ko, H.L.,Shen, M.X.,Ren, E.C. Activating killer cell immunoglobulin-like receptor 2DS2 binds to HLA-A*11 Proc.Natl.Acad.Sci.USA, 111:2662-2667, 2014 Cited by PubMed: 24550293DOI: 10.1073/pnas.1322052111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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