4N8V

Crystal structure of killer cell immunoglobulin-like receptor KIR2DS2 in complex with HLA-A

4N8V の概要

• エントリーDOI: 10.2210/pdb4n8v/pdb
• 分子名称: Killer cell immunoglobulin-like receptor 2DS2, HLA class I histocompatibility antigen, A-11 alpha chain, Beta-2-microglobulin, ... (5 entities in total)
• 機能のキーワード: antigen presentation, cell lysing, kir binding, membrane, kir2ds2, activating kir, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P43631; Secreted: P13746; Virion membrane; Multi-pass membrane protein (Potential): P61769; Cell membrane; Single-pass type I membrane protein: Q76ZQ3
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 133829.00

構造登録者

Liu, J.X.,Ren, E.C. (登録日: 2013-10-18, 公開日: 2014-02-05, 最終更新日: 2023-11-08)

• 主引用文献: Liu, J.X.,Xiao, Z.W.,Ko, H.L.,Shen, M.X.,Ren, E.C.; Activating killer cell immunoglobulin-like receptor 2DS2 binds to HLA-A*11; Proc.Natl.Acad.Sci.USA, 111:2662-2667, 2014; PubMed: 24550293; DOI: 10.1073/pnas.1322052111

実験手法

X-RAY DIFFRACTION (2.5 Å)