4N6D

Crystal structure of a TRAP periplasmic solute binding protein from Desulfovibrio salexigens DSM2638 (Desal_3247), Target EFI-510112, phased with I3C, open complex, C-terminus of symmetry mate bound in ligand binding site

Summary for 4N6D

• Entry DOI: 10.2210/pdb4n6d/pdb
• Descriptor: TRAP dicarboxylate transporter-DctP subunit, 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: trap periplasmic solute binding family, enzyme function initiative, efi, structural genomics, transport protein
• Biological source: Desulfovibrio salexigens
• Total number of polymer chains: 1
• Total formula weight: 39495.41

Authors

Vetting, M.W.,Al Obaidi, N.F.,Stead, M.,Attonito, J.D.,Scott Glenn, A.,Chowdhury, S.,Evans, B.,Hillerich, B.,Love, J.,Seidel, R.D.,Imker, H.J.,Gerlt, J.A.,Almo, S.C.,Enzyme Function Initiative (EFI) (deposition date: 2013-10-11, release date: 2013-10-30, Last modification date: 2024-02-28)

• Primary citation: Vetting, M.W.,Al-Obaidi, N.,Zhao, S.,San Francisco, B.,Kim, J.,Wichelecki, D.J.,Bouvier, J.T.,Solbiati, J.O.,Vu, H.,Zhang, X.,Rodionov, D.A.,Love, J.D.,Hillerich, B.S.,Seidel, R.D.,Quinn, R.J.,Osterman, A.L.,Cronan, J.E.,Jacobson, M.P.,Gerlt, J.A.,Almo, S.C.; Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.; Biochemistry, 54:909-931, 2015; PubMed: 25540822; DOI: 10.1021/bi501388y

Experimental method

X-RAY DIFFRACTION (1.701 Å)