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4N0N

Crystal structure of Arterivirus nonstructural protein 10 (helicase)

Summary for 4N0N
Entry DOI10.2210/pdb4n0n/pdb
Related4N0O
DescriptorReplicase polyprotein 1ab, ZINC ION, SULFATE ION, ... (5 entities in total)
Functional Keywordsarterivirus, helicase, zbd, nsp10, hydrolase
Biological sourceEquine arteritis virus (EAV)
Cellular locationNsp1 papain-like cysteine proteinase: Host nucleus. Nsp2 cysteine proteinase: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 5-6-7: Host membrane; Multi-pass membrane protein (Potential). 3C-like serine proteinase: Host cytoplasm (Potential). RNA-directed RNA polymerase: Host cytoplasm, host perinuclear region (Potential). Helicase: Host cytoplasm, host perinuclear region (Potential): P19811
Total number of polymer chains1
Total formula weight46356.23
Authors
Deng, Z.,Chen, Z. (deposition date: 2013-10-02, release date: 2014-01-08, Last modification date: 2024-02-28)
Primary citationDeng, Z.,Lehmann, K.C.,Li, X.,Feng, C.,Wang, G.,Zhang, Q.,Qi, X.,Yu, L.,Zhang, X.,Feng, W.,Wu, W.,Gong, P.,Tao, Y.,Posthuma, C.C.,Snijder, E.J.,Gorbalenya, A.E.,Chen, Z.
Structural basis for the regulatory function of a complex zinc-binding domain in a replicative arterivirus helicase resembling a nonsense-mediated mRNA decay helicase.
Nucleic Acids Res., 42:3464-3477, 2014
Cited by
PubMed: 24369429
DOI: 10.1093/nar/gkt1310
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

217705

數據於2024-03-27公開中

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