Crystal Structure of Biotin Carboxylase form Haemophilus influenzae in Complex with Phosphonoformate

Summary for 4MV7

Related1DV1 2VR1 4MV1 4MV3 4MV4 4MV6 4MV8 4MV9
DescriptorBiotin carboxylase, PHOSPHONOFORMIC ACID, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordsatp-grasp, ligase
Biological sourceHaemophilus influenzae
Total number of polymer chains1
Total molecular weight51596.7
Broussard, T.C.,Pakhomova, S.,Neau, D.B.,Champion, T.S.,Bonnot, R.J.,Waldrop, G.L. (deposition date: 2013-09-23, release date: 2015-01-14, Last modification date: 2017-11-15)
Primary citation
Broussard, T.C.,Pakhomova, S.,Neau, D.B.,Bonnot, R.,Waldrop, G.L.
Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase.
Biochemistry, 54:3860-3870, 2015
PubMed: 26020841 (PDB entries with the same primary citation)
DOI: 10.1021/acs.biochem.5b00340
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.202100.2%1.2%13.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report