4MUB

Schistosoma mansoni (Blood Fluke) Sulfotransferase/Oxamniquine Complex

4MUB の概要

• エントリーDOI: 10.2210/pdb4mub/pdb
• 分子名称: Sulfotransferase, ADENOSINE-3'-5'-DIPHOSPHATE, {(2S)-7-nitro-2-[(propan-2-ylamino)methyl]-1,2,3,4-tetrahydroquinolin-6-yl}methanol, ... (4 entities in total)
• 機能のキーワード: pap, oxamniquine, parasite, helminth, drug resistance, transferase
• 由来する生物種: Schistosoma mansoni (Blood fluke)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 30683.10

構造登録者

Valentim, C.L.L.,Cioli, D.,Chevalier, F.D.,Cao, X.,Taylor, A.B.,Holloway, S.P.,Pica-Mattoccia, L.,Guidi, A.,Basso, A.,Tsai, I.J.,Berriman, M.,Carvalho-Queiroz, C.,Almeida, M.,Aguilar, H.,Frantz, D.E.,Hart, P.J.,Anderson, T.J.C.,LoVerde, P.T. (登録日: 2013-09-21, 公開日: 2013-12-18, 最終更新日: 2024-02-28)

• 主引用文献: Valentim, C.L.,Cioli, D.,Chevalier, F.D.,Cao, X.,Taylor, A.B.,Holloway, S.P.,Pica-Mattoccia, L.,Guidi, A.,Basso, A.,Tsai, I.J.,Berriman, M.,Carvalho-Queiroz, C.,Almeida, M.,Aguilar, H.,Frantz, D.E.,Hart, P.J.,LoVerde, P.T.,Anderson, T.J.; Genetic and molecular basis of drug resistance and species-specific drug action in schistosome parasites.; Science, 342:1385-1389, 2013; PubMed: 24263136; DOI: 10.1126/science.1243106

実験手法

X-RAY DIFFRACTION (1.75 Å)