4MSS
Crystal structure of Burkholderia cenocepacia family 3 glycoside hydrolase (NagZ) bound to (3S,4R,5R,6S)-3-acetamido-4,5,6-trihydroxyazepane
Summary for 4MSS
Entry DOI | 10.2210/pdb4mss/pdb |
Related | 4G6C 4GNV |
Descriptor | Beta-hexosaminidase 1, N-[(3S,4R,5R,6S)-4,5,6-trihydroxyazepan-3-yl]acetamide, GLYCEROL, ... (4 entities in total) |
Functional Keywords | tim barrel, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Burkholderia cenocepacia |
Total number of polymer chains | 2 |
Total formula weight | 76918.26 |
Authors | Vadlamani, G.,Mark, B.L. (deposition date: 2013-09-18, release date: 2013-10-30, Last modification date: 2023-09-20) |
Primary citation | Mondon, M.,Hur, S.,Vadlamani, G.,Rodrigues, P.,Tsybina, P.,Oliver, A.,Mark, B.L.,Vocadlo, D.J.,Bleriot, Y. Selective trihydroxyazepane NagZ inhibitors increase sensitivity of Pseudomonas aeruginosa to beta-lactams. Chem.Commun.(Camb.), 49:10983-10985, 2013 Cited by PubMed: 24136176DOI: 10.1039/c3cc46646a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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