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4MJV

Influenza Neuraminidase in complex with a novel antiviral compound

Summary for 4MJV
Entry DOI10.2210/pdb4mjv/pdb
Related4MJU
DescriptorNeuraminidase, (2E,5S,9R,10S)-10-(acetylamino)-2-imino-4-oxo-9-(pentan-3-yloxy)-1-thia-3-azaspiro[4.5]dec-6-ene-7-carboxylic acid, CALCIUM ION, ... (4 entities in total)
Functional Keywordsneuraminidase, sialidase, viral protein, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceInfluenza A virus
Cellular locationVirion membrane : Q07599
Total number of polymer chains1
Total formula weight43592.08
Authors
Kerry, P.S. (deposition date: 2013-09-04, release date: 2014-01-15, Last modification date: 2017-11-15)
Primary citationMohan, S.,Kerry, P.S.,Bance, N.,Niikura, M.,Pinto, B.M.
Serendipitous discovery of a potent influenza virus a neuraminidase inhibitor.
Angew.Chem.Int.Ed.Engl., 53:1076-1080, 2014
Cited by
PubMed: 24339250
DOI: 10.1002/anie.201308142
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.65 Å)
Structure validation

217705

건을2024-03-27부터공개중

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