4MHF

Crystal structure of a TRAP periplasmic solute binding protein from Polaromonas sp. JS666 (Bpro_3107), target EFI-510173, with bound alpha/beta D-Glucuronate, space group P21

4MHF の概要

• エントリーDOI: 10.2210/pdb4mhf/pdb
• 関連するPDBエントリー: 4MIJ
• 分子名称: TRAP dicarboxylate transporter, DctP subunit, beta-D-glucopyranuronic acid, alpha-D-glucopyranuronic acid, ... (4 entities in total)
• 機能のキーワード: trap periplasmic solute binding family, enzyme function initiative, efi, structural genomics, transport protein
• 由来する生物種: Polaromonas
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 37110.64

構造登録者

Vetting, M.W.,Toro, R.,Bhosle, R.,Al Obaidi, N.F.,Morisco, L.L.,Wasserman, S.R.,Sojitra, S.,Zhao, S.,Stead, M.,Washington, E.,Scott Glenn, A.,Chowdhury, S.,Evans, B.,Hammonds, J.,Hillerich, B.,Love, J.,Seidel, R.D.,Imker, H.J.,Jacobson, M.P.,Gerlt, J.A.,Almo, S.C.,Enzyme Function Initiative (EFI) (登録日: 2013-08-29, 公開日: 2013-09-18, 最終更新日: 2020-07-29)

• 主引用文献: Vetting, M.W.,Al-Obaidi, N.,Zhao, S.,San Francisco, B.,Kim, J.,Wichelecki, D.J.,Bouvier, J.T.,Solbiati, J.O.,Vu, H.,Zhang, X.,Rodionov, D.A.,Love, J.D.,Hillerich, B.S.,Seidel, R.D.,Quinn, R.J.,Osterman, A.L.,Cronan, J.E.,Jacobson, M.P.,Gerlt, J.A.,Almo, S.C.; Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.; Biochemistry, 54:909-931, 2015; PubMed: 25540822; DOI: 10.1021/bi501388y

実験手法

X-RAY DIFFRACTION (1.46 Å)