4MEV

Crystal structure of a TRAP periplasmic solute binding protein from Rhodoferax ferrireducens (Rfer_1840), Target EFI-510211, with bound malonate, space group I422

Summary for 4MEV

• Entry DOI: 10.2210/pdb4mev/pdb
• Descriptor: TRAP dicarboxylate transporter-DctP subunit, CITRIC ACID, MALONATE ION, ... (4 entities in total)
• Functional Keywords: trap periplasmic solute binding family, enzyme function initiative, efi, structural genomics, transport protein
• Biological source: Rhodoferax ferrireducens
• Cellular location: Periplasm : Q21XD7
• Total number of polymer chains: 1
• Total formula weight: 38115.99

Authors

Vetting, M.W.,Toro, R.,Bhosle, R.,Al Obaidi, N.F.,Zhao, S.,Stead, M.,Washington, E.,Scott Glenn, A.,Chowdhury, S.,Evans, B.,Hammonds, J.,Hillerich, B.,Love, J.,Seidel, R.D.,Imker, H.J.,Jacobson, M.P.,Gerlt, J.A.,Almo, S.C.,Enzyme Function Initiative (EFI) (deposition date: 2013-08-27, release date: 2013-09-04, Last modification date: 2023-09-20)

• Primary citation: Vetting, M.W.,Al-Obaidi, N.,Zhao, S.,San Francisco, B.,Kim, J.,Wichelecki, D.J.,Bouvier, J.T.,Solbiati, J.O.,Vu, H.,Zhang, X.,Rodionov, D.A.,Love, J.D.,Hillerich, B.S.,Seidel, R.D.,Quinn, R.J.,Osterman, A.L.,Cronan, J.E.,Jacobson, M.P.,Gerlt, J.A.,Almo, S.C.; Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.; Biochemistry, 54:909-931, 2015; PubMed: 25540822; DOI: 10.1021/bi501388y

Experimental method

X-RAY DIFFRACTION (1.8 Å)