4MCV

Star 12 bound to analog-sensitive Src kinase

Summary for 4MCV

Entry DOI	10.2210/pdb4mcv/pdb
Descriptor	Proto-oncogene tyrosine-protein kinase Src, (7S)-12-(4-aminobutyl)-7-(2-methylpropyl)-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one (2 entities in total)
Functional Keywords	kinase domain, tyrosine kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Gallus gallus (bantam,chickens)
Cellular location	Cell membrane : P00523
Total number of polymer chains	2
Total formula weight	64534.39
Authors	Lopez, M.S.,Shokat, K.M. (deposition date: 2013-08-21, release date: 2013-11-20, Last modification date: 2024-02-28)
Primary citation	Lopez, M.S.,Choy, J.W.,Peters, U.,Sos, M.L.,Morgan, D.O.,Shokat, K.M. Staurosporine-derived inhibitors broaden the scope of analog-sensitive kinase technology. J.Am.Chem.Soc., 135:18153-18159, 2013 Cited by PubMed: 24171479 DOI: 10.1021/ja408704u PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.73 Å)

Structure validation