4LWB

Structure of Bacillus subtilis nitric oxide synthase in complex with 6-((((3R,5S)-5-(((6-amino-4-methylpyridin-2-yl)methoxy)methyl)pyrrolidin-3-yl)oxy)methyl)-4-methylpyridin-2-amine

Summary for 4LWB

Entry DOI	10.2210/pdb4lwb/pdb
Related	4LUW 4LUX 4LWA
Descriptor	Nitric oxide synthase oxygenase, PROTOPORPHYRIN IX CONTAINING FE, 6-({[(3R,5S)-5-{[(6-amino-4-methylpyridin-2-yl)methoxy]methyl}pyrrolidin-3-yl]oxy}methyl)-4-methylpyridin-2-amine, ... (7 entities in total)
Functional Keywords	nitric oxide synthase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological source	Bacillus subtilis subsp. subtilis
Total number of polymer chains	1
Total formula weight	43314.00
Authors	Holden, J.K.,Li, H.,Poulos, T.L. (deposition date: 2013-07-26, release date: 2013-10-23, Last modification date: 2023-09-20)
Primary citation	Holden, J.K.,Li, H.,Jing, Q.,Kang, S.,Richo, J.,Silverman, R.B.,Poulos, T.L. Structural and biological studies on bacterial nitric oxide synthase inhibitors. Proc.Natl.Acad.Sci.USA, 110:18127-18131, 2013 Cited by PubMed: 24145412 DOI: 10.1073/pnas.1314080110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation