4LVN

Crystal structure of PfSUB1-prodomain-NIMP.M7 Fab complex

Summary for 4LVN

Entry DOI	10.2210/pdb4lvn/pdb
Descriptor	Subtilisin-like serine protease, NIMP.M7 Fab light chain, NIMP.M7 Fab heavy chain, ... (7 entities in total)
Functional Keywords	alpha beta, enzyme-prodomain complex, rossmann fold, serine protease, calcium ions, prodomain, parasitophorous vacuole, hydrolase-inhibitor-immune system complex, hydrolase/inhibitor/immune system
Biological source	Plasmodium falciparum More
Total number of polymer chains	4
Total formula weight	96076.73
Authors	Withers-Martinez, C.,Blackman, M.J. (deposition date: 2013-07-26, release date: 2014-05-07, Last modification date: 2023-09-20)
Primary citation	Withers-Martinez, C.,Strath, M.,Hackett, F.,Haire, L.F.,Howell, S.A.,Walker, P.A.,Evangelos, C.,Dodson, G.G.,Blackman, M.J. The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin. Nat Commun, 5:3726-3726, 2014 Cited by PubMed: 24785947 DOI: 10.1038/ncomms4726 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation