4LRS

Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site

4LRS の概要

• エントリーDOI: 10.2210/pdb4lrs/pdb
• 関連するPDBエントリー: 4LRT
• 分子名称: 4-hydroxy-2-oxovalerate aldolase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, FORMYL GROUP, ... (12 entities in total)
• 機能のキーワード: rossmann fold, tim barrel domain, dehydrogenase, aldolase, oxidoreductase
• 由来する生物種: Thermomonospora curvata; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 73954.12

構造登録者

Fischer, B.,Branlant, G.,Talfournier, F.,Gruez, A. (登録日: 2013-07-20, 公開日: 2013-09-04, 最終更新日: 2023-11-15)

• 主引用文献: Fischer, B.,Branlant, G.,Talfournier, F.,Gruez, A.; Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site; To be Published,

実験手法

X-RAY DIFFRACTION (1.55 Å)