4LM9

Crystal structure of HCoV-OC43 N-NTD complexed with GMP

Summary for 4LM9

• Entry DOI: 10.2210/pdb4lm9/pdb
• Related: 4LM7 4LMC 4LMT
• Descriptor: Nucleoprotein, GUANOSINE-5'-MONOPHOSPHATE (3 entities in total)
• Functional Keywords: hcov-oc43 nucleocapsid protein, n-terminal domain, rna binding, rna binding protein
• Biological source: Human coronavirus (HCoV-OC43)
• Cellular location: Virion: Q6SA23
• Total number of polymer chains: 1
• Total formula weight: 15714.04

Authors

Lin, S.Y.,Liu, C.L.,Hou, M.H. (deposition date: 2013-07-10, release date: 2014-05-28, Last modification date: 2023-11-08)

• Primary citation: Lin, S.Y.,Liu, C.L.,Chang, Y.M.,Zhao, J.,Perlman, S.,Hou, M.H.; Structural basis for the identification of the N-terminal domain of coronavirus nucleocapsid protein as an antiviral target; J.Med.Chem., 57:2247-2257, 2014; PubMed: 24564608; DOI: 10.1021/jm500089r

Experimental method

X-RAY DIFFRACTION (1.601 Å)