4LKD

Crystal Structure of Pseudomonas aeruginosa Lectin LecA Complexed with GalA-QRS at 2.31 A Resolution

Summary for 4LKD

• Entry DOI: 10.2210/pdb4lkd/pdb
• Related: 4LKE 4LKF
• Descriptor: PA-I galactophilic lectin, peptide QRSA, beta-D-galactopyranose, ... (6 entities in total)
• Functional Keywords: lectin fold, sugar binding protein, galactose, sugar binding protein-inhibitor complex, sugar binding protein/inhibitor
• Biological source: Pseudomonas aeruginosa; More
• Cellular location: Cytoplasm: Q05097
• Total number of polymer chains: 16
• Total formula weight: 108719.88

Authors

Kadam, R.U.,Stocker, A.,Reymond, J.-L. (deposition date: 2013-07-07, release date: 2013-12-18, Last modification date: 2020-07-29)

• Primary citation: Kadam, R.U.,Bergmann, M.,Garg, D.,Gabrieli, G.,Stocker, A.,Darbre, T.,Reymond, J.-L.; Structure-Based Optimization of the Terminal Tripeptide in Glycopeptide Dendrimer Inhibitors of Pseudomonas aeruginosa Biofilms Targeting LecA.; Chemistry, 19:17054-17063, 2013; PubMed: 24307364; DOI: 10.1002/chem.201302587

Experimental method

X-RAY DIFFRACTION (2.307 Å)