4LEE
Structure of the Als3 adhesin from Candida albicans, residues 1-313 (mature sequence), triple mutant in the binding cavity: K59M, A116V, Y301F
Summary for 4LEE
| Entry DOI | 10.2210/pdb4lee/pdb |
| Related | 4LE8 4LEB |
| Descriptor | Agglutinin-like protein 3 (1 entity in total) |
| Functional Keywords | adhesin, peptide binding protein, biofilm formation, cellular adhesion, peptides, cell surface, cell adhesion |
| Biological source | Candida albicans (Yeast) |
| Cellular location | Cell membrane (By similarity); Lipid-anchor, GPI-anchor (By similarity): O74623 |
| Total number of polymer chains | 4 |
| Total formula weight | 134837.19 |
| Authors | Lin, J.,Garnett, J.A.,Cota, E. (deposition date: 2013-06-25, release date: 2014-05-14, Last modification date: 2023-09-20) |
| Primary citation | Lin, J.,Oh, S.H.,Jones, R.,Garnett, J.A.,Salgado, P.S.,Rusnakova, S.,Matthews, S.J.,Hoyer, L.L.,Cota, E. The Peptide-binding Cavity Is Essential for Als3-mediated Adhesion of Candida albicans to Human Cells. J.Biol.Chem., 289:18401-18412, 2014 Cited by PubMed: 24802757DOI: 10.1074/jbc.M114.547877 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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