4LEB

Structure of the Als3 adhesin from Candida albicans, residues 1-299 (mature sequence) in complex with hepta-threonine

Summary for 4LEB

• Entry DOI: 10.2210/pdb4leb/pdb
• Related: 4LE8 4LEE
• Descriptor: Agglutinin-like protein 3, hepta-threonine (3 entities in total)
• Functional Keywords: adhesin, peptide binding protein, biofilm formation, cellular adhesion, peptides, cell surface, cell adhesion
• Biological source: Candida albicans (Yeast); More
• Cellular location: Cell membrane (By similarity); Lipid-anchor, GPI-anchor (By similarity): O74623
• Total number of polymer chains: 2
• Total formula weight: 33121.59

Authors

Lin, J.,Garnett, J.A.,Cota, E. (deposition date: 2013-06-25, release date: 2014-05-14, Last modification date: 2023-09-20)

• Primary citation: Lin, J.,Oh, S.H.,Jones, R.,Garnett, J.A.,Salgado, P.S.,Rusnakova, S.,Matthews, S.J.,Hoyer, L.L.,Cota, E.; The Peptide-binding Cavity Is Essential for Als3-mediated Adhesion of Candida albicans to Human Cells.; J.Biol.Chem., 289:18401-18412, 2014; PubMed: 24802757; DOI: 10.1074/jbc.M114.547877

Experimental method

X-RAY DIFFRACTION (1.4 Å)