Crystal structure of Cordyceps militaris IDCase H195A mutant

Summary for 4LAN

Related4LAK 4LAL 4LAM 4LAO
DescriptorUracil-5-carboxylate decarboxylase, ZINC ION (3 entities in total)
Functional Keywordspyrimidine metabolism, idcase, decarboxylase, uracil, dna decarboxylation, lyase
Biological sourceCordyceps militaris
Total number of polymer chains2
Total molecular weight81438.58
Xu, S.,Li, W.,Zhu, J.,Ding, J. (deposition date: 2013-06-20, release date: 2013-10-02, Last modification date: 2017-11-15)
Primary citation
Xu, S.,Li, W.,Zhu, J.,Wang, R.,Li, Z.,Xu, G.L.,Ding, J.
Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23:1296-1309, 2013
PubMed: 23917530 (PDB entries with the same primary citation)
DOI: 10.1038/cr.2013.107
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.1910 0.7% 2.7% 10.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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