4LA6

Crystal structure of 2-methylisoborneol synthase from Streptomyces coelicolor A3(2) in complex with Mg2+ and 2-fluoroneryl diphosphate

Summary for 4LA6

Entry DOI	10.2210/pdb4la6/pdb
Related	3V1V 3V1X 4LA5
Descriptor	2-methylisoborneol synthase, MAGNESIUM ION, (2E)-2-fluoro-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate, ... (4 entities in total)
Functional Keywords	terpenoid biosynthesis, biosynthesis, isoprenoid synthase fold, lyase
Biological source	Streptomyces coelicolor
Total number of polymer chains	1
Total formula weight	50525.71
Authors	Koksal, M.,Christianson, D.W. (deposition date: 2013-06-19, release date: 2013-07-31, Last modification date: 2023-09-20)
Primary citation	Koksal, M.,Chou, W.K.,Cane, D.E.,Christianson, D.W. Unexpected reactivity of 2-fluorolinalyl diphosphate in the active site of crystalline 2-methylisoborneol synthase. Biochemistry, 52:5247-5255, 2013 Cited by PubMed: 23844678 DOI: 10.1021/bi400797c PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.001 Å)

Structure validation