4L5W
Structural implications of the secondary CO2 binding pocket in human carbonic anhydrase II
Summary for 4L5W
Entry DOI | 10.2210/pdb4l5w/pdb |
Related | 4L5U 4L5V |
Descriptor | Carbonic anhydrase 2, ZINC ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | allosteric regulation, thermostability, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29486.58 |
Authors | Boone, C.D.,Gill, S.,McKenna, R. (deposition date: 2013-06-11, release date: 2014-04-30, Last modification date: 2024-02-28) |
Primary citation | Boone, C.D.,Gill, S.,Tu, C.,Silverman, D.N.,McKenna, R. Structural, catalytic and stabilizing consequences of aromatic cluster variants in human carbonic anhydrase II. Arch.Biochem.Biophys., 539:31-37, 2013 Cited by PubMed: 24036123DOI: 10.1016/j.abb.2013.09.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
Download full validation report