4L5F

Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII

4L5F の概要

• エントリーDOI: 10.2210/pdb4l5f/pdb
• 分子名称: Heavy chain of E106 antibody (VH and CH1 of IgG2c), Envelope protein, Light chain of E106 antibody (kappa), ... (4 entities in total)
• 機能のキーワード: antibody, fab, neutralizing, virus, envelope, viral protein, immune system, antibody epitope, infectious disease, center for structural genomics of infectious diseases (csgid), niaid, national institute of allergy and infectious diseases
• 由来する生物種: Dengue virus 1; 詳細
• 細胞内の位置: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Host endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Host endoplasmic reticulum membrane ; Peripheral membrane protein ; Lumenal side . Host nucleus . Secreted . Virion membrane ; Multi-pass membrane protein : Q8BE40
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 59089.08

構造登録者

Edeling, M.A.,Nelson, C.A.,Fremont, D.H.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2013-06-11, 公開日: 2013-12-11, 最終更新日: 2017-11-15)

• 主引用文献: Edeling, M.A.,Austin, S.K.,Shrestha, B.,Dowd, K.A.,Mukherjee, S.,Nelson, C.A.,Johnson, S.,Mabila, M.N.,Christian, E.A.,Rucker, J.,Pierson, T.C.,Diamond, M.S.,Fremont, D.H.; Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII; To be Published,

実験手法

X-RAY DIFFRACTION (2.45 Å)