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4KXW

Human transketolase in covalent complex with donor ketose D-xylulose-5-phosphate, crystal 2

Summary for 4KXW
Entry DOI10.2210/pdb4kxw/pdb
DescriptorTransketolase, MAGNESIUM ION, 1,2-ETHANEDIOL, ... (7 entities in total)
Functional Keywordsthiamin diphosphate, enzyme catalysis, pentose phosphate pathway, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight71329.14
Authors
Neumann, P.,Luedtke, S.,Ficner, R.,Tittmann, K. (deposition date: 2013-05-28, release date: 2013-08-21, Last modification date: 2023-09-20)
Primary citationLudtke, S.,Neumann, P.,Erixon, K.M.,Leeper, F.,Kluger, R.,Ficner, R.,Tittmann, K.
Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate.
Nat Chem, 5:762-767, 2013
Cited by
PubMed: 23965678
DOI: 10.1038/nchem.1728
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (0.97 Å)
Structure validation

217705

數據於2024-03-27公開中

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