4KXV

Human transketolase in covalent complex with donor ketose D-xylulose-5-phosphate, crystal 1

Summary for 4KXV

Entry DOI	10.2210/pdb4kxv/pdb
Descriptor	Transketolase, CALCIUM ION, 1,2-ETHANEDIOL, ... (6 entities in total)
Functional Keywords	thiamin diphosphate, enzyme catalysis, pentose phosphate pathway, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	70903.59
Authors	Neumann, P.,Luedtke, S.,Ficner, R.,Tittmann, K. (deposition date: 2013-05-28, release date: 2013-08-21, Last modification date: 2023-09-20)
Primary citation	Ludtke, S.,Neumann, P.,Erixon, K.M.,Leeper, F.,Kluger, R.,Ficner, R.,Tittmann, K. Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate. Nat Chem, 5:762-767, 2013 Cited by PubMed: 23965678 DOI: 10.1038/nchem.1728 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (0.97 Å)

Structure validation