4KXJ

Crystal structure of HCoV-OC43 N-NTD complexed with PJ34

Summary for 4KXJ

• Entry DOI: 10.2210/pdb4kxj/pdb
• Descriptor: Nucleoprotein, N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE (3 entities in total)
• Functional Keywords: hcov-oc43 n-ntd, rna binding protein, n-protein ligand
• Biological source: Human coronavirus (HCoV-OC43)
• Cellular location: Virion: Q6SA23
• Total number of polymer chains: 1
• Total formula weight: 15733.24

Authors

Lin, S.Y.,Hou, M.H. (deposition date: 2013-05-27, release date: 2014-05-28, Last modification date: 2024-03-20)

• Primary citation: Lin, S.Y.,Liu, C.L.,Chang, Y.M.,Zhao, J.,Perlman, S.,Hou, M.H.; Structural basis for the identification of the N-terminal domain of coronavirus nucleocapsid protein as an antiviral target; J.Med.Chem., 57:2247-2257, 2014; PubMed: 24564608; DOI: 10.1021/jm500089r

Experimental method

X-RAY DIFFRACTION (2.65 Å)