4KSY
Crystal structure of STING in complex with cGAMP
Summary for 4KSY
Entry DOI | 10.2210/pdb4ksy/pdb |
Descriptor | Stimulator of interferon genes protein, cGAMP (3 entities in total) |
Functional Keywords | innate immunity, immune system |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 27855.06 |
Authors | Zhang, X.,Chen, Z.J.,Zhang, X.W. (deposition date: 2013-05-18, release date: 2013-06-12, Last modification date: 2024-02-28) |
Primary citation | Zhang, X.,Shi, H.,Wu, J.,Zhang, X.,Sun, L.,Chen, C.,Chen, Z.J. Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING. Mol.Cell, 51:226-235, 2013 Cited by PubMed: 23747010DOI: 10.1016/j.molcel.2013.05.022 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.881 Å) |
Structure validation
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