4KSE

Crystal structure of a HIV p51 (219-230) deletion mutant

4KSE の概要

• エントリーDOI: 10.2210/pdb4kse/pdb
• 分子名称: HIV p51 subunit, 1,2-ETHANEDIOL (3 entities in total)
• 機能のキーワード: p51 subunit, hiv, aids, transferase
• 由来する生物種: Human immunodeficiency virus type 1 group M subtype B (HIV-1)
• 細胞内の位置: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P04585
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 48816.95

構造登録者

Zheng, X.,Mueller, G.A.,Derose, E.F.,Pedersen, L.C.,Gabel, S.A.,Cuneo, M.J.,Krahn, J.M.,London, R.E. (登録日: 2013-05-17, 公開日: 2014-08-13, 最終更新日: 2023-09-20)

• 主引用文献: Zheng, X.,Pedersen, L.C.,Gabel, S.A.,Mueller, G.A.,Cuneo, M.J.,DeRose, E.F.,Krahn, J.M.,London, R.E.; Selective unfolding of one Ribonuclease H domain of HIV reverse transcriptase is linked to homodimer formation.; Nucleic Acids Res., 42:5361-5377, 2014; PubMed: 24574528; DOI: 10.1093/nar/gku143

実験手法

X-RAY DIFFRACTION (2.677 Å)