4KR0

Complex structure of MERS-CoV spike RBD bound to CD26

4KR0 の概要

• エントリーDOI: 10.2210/pdb4kr0/pdb
• 関連するPDBエントリー: 4KQZ
• 分子名称: Dipeptidyl peptidase 4, S protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: 8-bladed beta-propeller domain, alpha/beta hydrolase domain, blades iv and v, cd26 beta-propeller, hydrolase-viral protein complex, hydrolase/viral protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 116101.53

構造登録者

Lu, G.,Hu, Y.,Wang, Q.,Qi, J.,Gao, F.,Li, Y.,Zhang, Y.,Zhang, W.,Yuan, Y.,Zhang, B.,Shi, Y.,Yan, J.,Gao, G.F. (登録日: 2013-05-15, 公開日: 2013-07-10, 最終更新日: 2023-11-08)

• 主引用文献: Lu, G.,Hu, Y.,Wang, Q.,Qi, J.,Gao, F.,Li, Y.,Zhang, Y.,Zhang, W.,Yuan, Y.,Bao, J.,Zhang, B.,Shi, Y.,Yan, J.,Gao, G.F.; Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26.; Nature, 500:227-231, 2013; PubMed: 23831647; DOI: 10.1038/nature12328

実験手法

X-RAY DIFFRACTION (2.702 Å)