4KPR

Tetrameric form of rat selenoprotein thioredoxin reductase 1

Summary for 4KPR

• Entry DOI: 10.2210/pdb4kpr/pdb
• Related: 1H6V 3EAN 3EAO
• Descriptor: Thioredoxin reductase 1, cytoplasmic, SULFITE ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total)
• Functional Keywords: selenoprotein, mammalian thioredoxin reductase 1, selenocysteine, fad, flavoprotein, oxidoreductase, redox-active center, nadp, antioxidant
• Biological source: Rattus norvegicus (rat)
• Cellular location: Cytoplasm (By similarity): O89049
• Total number of polymer chains: 4
• Total formula weight: 223519.11

Authors

Lindqvist, Y.,Sandalova, T.,Xu, J.,Arner, E. (deposition date: 2013-05-14, release date: 2014-05-14, Last modification date: 2023-09-20)

• Primary citation: Xu, J.,Eriksson, S.E.,Cebula, M.,Sandalova, T.,Hedstrom, E.,Pader, I.,Cheng, Q.,Myers, C.R.,Nagy, P.,Hellman, U.,Selivanova, G.,Lindqvist, Y.,J Arner, E.S.; The Trp114 residue of thioredoxin reductase 1 is an electron relay sensor for oxidative stress; To be Published, 2013

Experimental method

X-RAY DIFFRACTION (2.4 Å)